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Pattern Formation in the Cerebellum (Colloquium the Developing Brain)

Pattern Formation in the Cerebellum (Colloquium the Developing Brain)

Carol Armstrong
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Pattern formation has fascinated biologists since the time of Aristotle, but only recently have new tools begun to reveal the underlying mechanisms that create these patterns during development. In particular, the central nervous system is dynamically patterned and highly modular, ranging from nuclear cell clusters in the brain stem and spinal cord to the elaborate cytoarchitecture of the neocortex. Similar developmental processes divide brain structures such as the cerebral cortex, basal ganglia, superior colliculus, and cerebellum into these sub-compartments. The way neural modules form and the mechanisms that establish connectivity between these modules is one of the most complex problems in neuroscience and also one of the most important. This monograph focuses on pattern formation in the developing cerebellum. Table of Background and Rationale / Overview of Cerebellar Organization / The Modular Cerebellum / Overview of Cerebellar Development / Establishment and Organization of the Cerebellar Anlage / Development and Patterning of Purkinje Cells / Development and Patterning of Granule Cells / Development of Afferent Projections / Patterning of Other Cells in the Inhibitory Interneurons, Unipolar Brush Cells, and Glia / Neural Cell Death in Normal Development / Conclusion and Summary / Author Biographies
Language
English
Pages
138
Format
Paperback
Release
October 01, 2013
ISBN 13
9781615044566

Pattern Formation in the Cerebellum (Colloquium the Developing Brain)

Carol Armstrong
0/5 ( ratings)
Read Download
Pattern formation has fascinated biologists since the time of Aristotle, but only recently have new tools begun to reveal the underlying mechanisms that create these patterns during development. In particular, the central nervous system is dynamically patterned and highly modular, ranging from nuclear cell clusters in the brain stem and spinal cord to the elaborate cytoarchitecture of the neocortex. Similar developmental processes divide brain structures such as the cerebral cortex, basal ganglia, superior colliculus, and cerebellum into these sub-compartments. The way neural modules form and the mechanisms that establish connectivity between these modules is one of the most complex problems in neuroscience and also one of the most important. This monograph focuses on pattern formation in the developing cerebellum. Table of Background and Rationale / Overview of Cerebellar Organization / The Modular Cerebellum / Overview of Cerebellar Development / Establishment and Organization of the Cerebellar Anlage / Development and Patterning of Purkinje Cells / Development and Patterning of Granule Cells / Development of Afferent Projections / Patterning of Other Cells in the Inhibitory Interneurons, Unipolar Brush Cells, and Glia / Neural Cell Death in Normal Development / Conclusion and Summary / Author Biographies
Language
English
Pages
138
Format
Paperback
Release
October 01, 2013
ISBN 13
9781615044566

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